JPS60104037A - １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 - Google Patents
１，４−ジヒドロキシ−２−ナフトエ酸の製造方法Info
- Publication number
- JPS60104037A JPS60104037A JP21142583A JP21142583A JPS60104037A JP S60104037 A JPS60104037 A JP S60104037A JP 21142583 A JP21142583 A JP 21142583A JP 21142583 A JP21142583 A JP 21142583A JP S60104037 A JPS60104037 A JP S60104037A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- water
- alkali metal
- pressure
- nhq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 15
- VOJUXHHACRXLTD-UHFFFAOYSA-N 1,4-dihydroxy-2-naphthoic acid Chemical compound C1=CC=CC2=C(O)C(C(=O)O)=CC(O)=C21 VOJUXHHACRXLTD-UHFFFAOYSA-N 0.000 title claims 4
- 238000006243 chemical reaction Methods 0.000 claims abstract description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 150000001339 alkali metal compounds Chemical class 0.000 claims abstract description 11
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 28
- 239000001569 carbon dioxide Substances 0.000 claims description 14
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 14
- 238000001816 cooling Methods 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 9
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract description 7
- 238000006473 carboxylation reaction Methods 0.000 abstract description 6
- 239000011541 reaction mixture Substances 0.000 abstract description 5
- PCILLCXFKWDRMK-UHFFFAOYSA-N naphthalene-1,4-diol Chemical compound C1=CC=C2C(O)=CC=C(O)C2=C1 PCILLCXFKWDRMK-UHFFFAOYSA-N 0.000 abstract description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract description 3
- 238000003756 stirring Methods 0.000 abstract description 3
- 238000000354 decomposition reaction Methods 0.000 abstract description 2
- 239000000975 dye Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 239000000049 pigment Substances 0.000 abstract description 2
- 235000017550 sodium carbonate Nutrition 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010791 quenching Methods 0.000 abstract 1
- 230000000171 quenching effect Effects 0.000 abstract 1
- VOJUXHHACRXLTD-UHFFFAOYSA-M 1,4-dihydroxy-2-naphthoate Chemical compound C1=CC=C2C(O)=CC(C([O-])=O)=C(O)C2=C1 VOJUXHHACRXLTD-UHFFFAOYSA-M 0.000 description 20
- 108010065780 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Proteins 0.000 description 20
- 108010089355 dihydroneopterin aldolase Proteins 0.000 description 20
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 9
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 8
- 239000000047 product Substances 0.000 description 5
- 229910000027 potassium carbonate Inorganic materials 0.000 description 4
- 235000011181 potassium carbonates Nutrition 0.000 description 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 229910052783 alkali metal Inorganic materials 0.000 description 3
- -1 alkali metal salt Chemical class 0.000 description 3
- 239000006227 byproduct Substances 0.000 description 3
- 235000015497 potassium bicarbonate Nutrition 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000012295 chemical reaction liquid Substances 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 2
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 2
- 239000011736 potassium bicarbonate Substances 0.000 description 2
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 230000021523 carboxylation Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 150000004679 hydroxides Chemical class 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 150000002736 metal compounds Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 150000003388 sodium compounds Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21142583A JPS60104037A (ja) | 1983-11-10 | 1983-11-10 | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21142583A JPS60104037A (ja) | 1983-11-10 | 1983-11-10 | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60104037A true JPS60104037A (ja) | 1985-06-08 |
| JPH0480893B2 JPH0480893B2 (en]) | 1992-12-21 |
Family
ID=16605738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP21142583A Granted JPS60104037A (ja) | 1983-11-10 | 1983-11-10 | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60104037A (en]) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599971A (en) * | 1992-01-17 | 1997-02-04 | Sumitomo Chemical Company, Limited | Method for producing 1,4-dihydroxy-2-naphthoic acid |
| EP1416052A4 (en) * | 2001-08-10 | 2005-10-12 | Meiji Dairies Corp | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROXY-2-NAPHTHOIC ACID |
| JP2009173563A (ja) * | 2008-01-22 | 2009-08-06 | Chiba Inst Of Technology | 芳香族ヒドロキシカルボン酸の製造方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57126443A (en) * | 1981-01-29 | 1982-08-06 | Nippon Shokubai Kagaku Kogyo Co Ltd | Preparation of 1,4-dihydroxy-2-naphthoic acid |
| JPS57128655A (en) * | 1981-02-02 | 1982-08-10 | Nippon Shokubai Kagaku Kogyo Co Ltd | Preparation of 1,4-dihydroxy-2-naphthoic acid |
-
1983
- 1983-11-10 JP JP21142583A patent/JPS60104037A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57126443A (en) * | 1981-01-29 | 1982-08-06 | Nippon Shokubai Kagaku Kogyo Co Ltd | Preparation of 1,4-dihydroxy-2-naphthoic acid |
| JPS57128655A (en) * | 1981-02-02 | 1982-08-10 | Nippon Shokubai Kagaku Kogyo Co Ltd | Preparation of 1,4-dihydroxy-2-naphthoic acid |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599971A (en) * | 1992-01-17 | 1997-02-04 | Sumitomo Chemical Company, Limited | Method for producing 1,4-dihydroxy-2-naphthoic acid |
| EP1416052A4 (en) * | 2001-08-10 | 2005-10-12 | Meiji Dairies Corp | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROXY-2-NAPHTHOIC ACID |
| US7374915B2 (en) | 2001-08-10 | 2008-05-20 | Meiji Dairies Corporation | Process for producing 1,4-dihydroxy-2-naphthoic acid |
| US7629155B2 (en) | 2001-08-10 | 2009-12-08 | Meiji Dairies Corporation | Process for producing 1,4-dihydroxy-2-naphthoic acid |
| US7834061B2 (en) | 2001-08-10 | 2010-11-16 | Meiji Dairies Corporation | Process for producing 1,4-dihydroxy-2-naphthoic acid |
| US8110607B2 (en) | 2001-08-10 | 2012-02-07 | Meiji Co., Ltd. | Process for producing 1,4-dihydroxy-2-naphthoic acid |
| JP2009173563A (ja) * | 2008-01-22 | 2009-08-06 | Chiba Inst Of Technology | 芳香族ヒドロキシカルボン酸の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0480893B2 (en]) | 1992-12-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3990475B2 (ja) | メチオニンおよびその塩の製造方法 | |
| US3833651A (en) | Process for the preparation of dl-methionine | |
| JPH0629225B2 (ja) | ジタ−シヤリ−ブチルジカ−ボネ−トの製法 | |
| JPS60104037A (ja) | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 | |
| JPS58116435A (ja) | ４−ヒドロキシ−２，４，６−トリメチルシクロヘキサ−２，５−ジエン−１−オンの製造法 | |
| JP2508773B2 (ja) | ジメチルアミノエタノ―ルの製造法 | |
| JPS61282355A (ja) | ４，４’−ジニトロスチルベン−２，２’−ジスルホン酸塩の製造法 | |
| JPS5925779B2 (ja) | 立体異性脂環ジアミンの異性化法 | |
| JPS63130588A (ja) | ２，４，５−トリアミノ−６−ヒドロキシピリミジンを製造する方法 | |
| US4507510A (en) | Process for producing xylyleneglycol | |
| JPS60228452A (ja) | 純粋２，６‐ジクロルベンゾニトリルの製造方法 | |
| JP2748170B2 (ja) | Ｏ―メチルイソ尿素塩の製法 | |
| JPS59141537A (ja) | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 | |
| JP3199618B2 (ja) | １，４−ジヒドロキシ−２−ナフトエ酸の製造方法 | |
| JPH0348637A (ja) | カルボン酸エステルとホルムアミドの製造法 | |
| US5081291A (en) | Process for manufacture of 3,3',4,4'-biphenyltetracarboxylic acid | |
| JP4087494B2 (ja) | １−アミノ−１−メチル−３（４）−アミノメチルシクロヘキサンの製造方法 | |
| JPS6035331B2 (ja) | キシリレングリコ−ルの製造法 | |
| US2640854A (en) | Process for the production of an aromatic amino hydroxy acid | |
| JPS59163331A (ja) | キシリレングリコ−ルの製造方法 | |
| JPS6125713B2 (en]) | ||
| JPS6217989B2 (en]) | ||
| JPS62129242A (ja) | 含フツ素α，β−不飽和カルボン酸の製造方法 | |
| JPH11180953A (ja) | インドール−３−カルボン酸の製造方法 | |
| JP2002308839A (ja) | ２−アミノ−４−ヒドロキシ安息香酸の製造方法 |